CJ has filed a patent for a modified polypeptide with xylanase activity. The polypeptide has specific sequence identity and modifications, enhancing its enzymatic function. The patent aims to utilize this modified polypeptide for various industrial applications. GlobalData’s report on CJ gives a 360-degree view of the company including its patenting strategy. Buy the report here.
According to GlobalData’s company profile on CJ, NSAID cancer drugs was a key innovation area identified from patents. CJ's grant share as of January 2024 was 40%. Grant share is based on the ratio of number of grants to total number of patents.
Modified xylanase polypeptide with specific amino acid substitutions
A recently filed patent (Publication Number: US20240035054A1) discloses a modified polypeptide with xylanase activity, featuring specific modifications to enhance its functionality. The modified polypeptide, with a sequence identity of 70% or more to a reference sequence, can include substitutions of amino acids at designated positions, formation of disulfide bonds, or a combination of both. These modifications aim to improve the polypeptide's thermal tolerance and stability compared to the original sequence. The patent also covers methods for producing xylo-oligosaccharides or xylose by utilizing the modified polypeptide in conjunction with a host cell or specific compositions for degrading xylan-containing materials effectively.
Furthermore, the patent encompasses the polynucleotide encoding the modified polypeptide, a host cell containing the modified polypeptide, and methods for preparing the modified polypeptide through cell culturing. The modifications detailed in the patent, such as specific amino acid substitutions and disulfide bridge formations, highlight the innovative approach to enhancing xylanase activity for various industrial applications. By providing a detailed framework for modifying the polypeptide and utilizing it in processes for xylo-oligosaccharide production and xylan-containing material degradation, the patent offers a comprehensive solution for improving enzymatic efficiency in relevant industries.
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