Kikkoman has patented a novel method for quantifying ethanolamine phosphate, a biomarker of depression. The method involves adding oxidoreductase to a sample, allowing it to act on the ethanolamine phosphate, and determining the concentration. The oxidoreductase used belongs to EC NO: 1.4 or EC NO: 1.5. GlobalData’s report on Kikkoman gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Kikkoman, Nanoemulsion cosmetics was a key innovation area identified from patents. Kikkoman's grant share as of January 2024 was 26%. Grant share is based on the ratio of number of grants to total number of patents.

Quantification method for ethanolamine phosphate using oxidoreductase

Source: United States Patent and Trademark Office (USPTO). Credit: Kikkoman Corp

The granted patent (Publication Number: US11879149B2) discloses a quantitation method for ethanolamine phosphate using an oxidoreductase enzyme. The method involves adding the oxidoreductase to a sample containing ethanolamine phosphate, allowing it to act on the substrate, and subsequently determining the concentration of ethanolamine phosphate in the sample. The oxidoreductase used in the method belongs to EC NO: 1.4 or EC NO: 1.5, with specific examples including primary amine dehydrogenase, monoamine dehydrogenase, diamine dehydrogenase, and others.

Furthermore, the method may include additional steps such as reducing a mediator by adding the oxidoreductase, and reacting the reduced mediator with a reagent to determine the concentration of ethanolamine phosphate. The oxidoreductase can also be an oxidase, with hydrogen peroxide produced by the oxidase reacting with a reagent to determine the concentration of ethanolamine phosphate. The patent covers various oxidoreductase enzymes and oxidases, including taurine dehydrogenase with a large subunit, for use in the quantitation method of ethanolamine phosphate. Overall, the patent provides a detailed and specific method for accurately measuring ethanolamine phosphate levels using specific oxidoreductase enzymes and oxidases.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.